santaris pharma pipeline

The Company is biology-driven with proprietary technology and a strong focus on product development. Roche (SIX: RO, ROG; OTCQX: RHHBY) has agreed to acquire Santaris Pharma, a privately held biopharmaceutical company based near Copenhagen, Denmark. Santaris Pharma is a biopharmaceutical company focused on the discovery and development of RNA-targeted therapies. These so-called Spiegelmers (the German word Spiegel means mirror) are highly specific for the pharmacologically relevant target for which they were selected. Edit Lists Featuring This Company Section, Specialty Active Pharmaceutical Ingredients (API) Market: Global Industry Analysis and Opportunity Assessment, 2016 - 2024, Ophthalmic Drugs Market Forecast 2016-2026, Pharma Leader Series: Top 25 Ophthalmic Drug Manufacturers 2016-2026, European Union (EU) Companies that Exited (Top 10K), Closed European Union (EU) Health Care Companies. capabilities to rapidly deliver potent single-stranded LNA-based drug candidates across a multitude of disease states. Directory of Companies. For further information, please contact Santaris Pharma: Dr Keith McCullagh, President & CEO, Santaris Pharma A/S, Copenhagen, Denmark. Santaris Pharma A/S - Product Pipeline Review - 2014 is a new market research publication announced by Reportstack. Since Gilde invested in Santaris Pharma, the company has advanced its product pipeline through the clinic and signed commercial collaboration agreements with GlaxoSmithKline, Pfizer, Bristol-Myers Squibb, Roche and Shire. Roche has just announced a $450m deal to acquire Danish company Santaris Pharma, a specialist in a form of antisense therapy that switches off a gene by interacting with messenger RNA (mRNA) to. Santaris Pharma A/S - Product Pipeline Review - 2014. Summary Miravirsen is an antimiR developed by Santaris Pharma and was the first drug that targets miRNA, which advanced to clinical trials. in addition to miravirsen, santaris pharma a/s has a robust product pipeline targeting mrnas and micrornas both internally as well as in partnerships and collaborations with miragen therapeutics (cardiovascular diseases), shire plc (rare genetic disorders), pfizer (undisclosed therapeutic areas), glaxosmithkline (viral disease) and enzon PDF. Veloxis Pharmaceuticals, Inc. Initiates Phase 1 Study of ART-123 in the U.S. and Japan. PDF. A pipeline with the potential to impact patient lives worldwide. COPENHAGEN, Denmark | November 10, 2008 | Santaris Pharma announced today that SPC3042, a RNA-based antisense oligonucleotide developed using the company's proprietary Locked Nucleic Acid (LNA) technology, potently blocks survivin, a key survival protein in cancer cells, in both in vitro and in vivo models of prostate cancer. You must have cookies enabled to login Arexis uses forward genetics for a high-resolution molecular dissection of causative disease mechanisms. About Antares; Medicines; For Partners; For Investors; For Patients; Careers; Contact Us Since Gilde invested in Santaris Pharma, the company has advanced its product pipeline through the clinic and signed commercial collaboration agreements with GlaxoSmithKline, Pfizer, Bristol-Myers Squibb, Roche and Shire. Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that it has agreed to acquire Santaris Pharma, a privately held biopharmaceutical company based near Copenhagen, Denmark. HISTORICAL PERFORMANCE: From 2014-2019 Merck's stock has grown at 1.3x the rate of AbbVie. About Santaris Pharma. . Our R&D activities are focused on applying excellent science to discover and develop potential new medicines with the goal of becoming first-in-class or best-in-class therapeutics. /PRNewswire/ -- Santaris Pharma A/S, a clinical-stage biopharmaceutical company focused on the research and development of mRNA and microRNA targeted. features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. Acute & chronic kidney injury We focus on a very specific protein (undisclosed) that plays a major role in inflammation / fibrosis. By using its proprietary Locked Nucleic Acid (:LNA) platform and tissue-targeting expertise, Santaris Pharma is developing a diverse pipeline of LNA therapeutics that influence the production or . Santaris Pharma has pioneered its proprietary Locked Nucleic Acid (LNA) platform that has contributed to an emerging era of RNA-targeting therapeutics. Santaris Pharma A/S is a privately held clinical-stage biopharmaceutical company focused on the discovery and development of RNA-targeted therapies. july 27, 2006 announced agreement with enzon pharmaceuticals, inc. plaintiff alleges santaris "sold two antisense gapmer molecules and targets to enzon for $6 million," ( id. +45 4517 9888 hs@santaris.com Back to news "HIF-1 alpha, as a target, has caught the imagination of the medical community for many years," Orum said. HYB_fib (dcRNA) BASEL, Switzerland I August 4, 2014 I Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that it has agreed to acquire Santaris Pharma, a privately held biopharmaceutical company based near Copenhagen, Denmark. [3] MedChemComm View Article Online Published on 01 August 2014. The core therapeutic focus of our company is obesity, Type II diabetes / metabolic syndrome, inflammatory diseases, and organ protection in severe cardiovascular diseases such as myocardial infarction and post-surgical organ failure. The method may offer new hope to allergy sufferers everywhere because it targets the source of the allergic reaction rather than the symptoms.This is achieved by eliminating IgE, an antibody causing the release of histamine which triggers the allergic reactions for many individuals. Santaris Pharma A/S advances a second drug from its cardiometabolic program, SPC4955, inhibiting apoB, into Phase 1 clinical trials for the treatment of high cholesterol. - As at June The popularity score combines profile views, clicks and the number of times the company appears in search results. By using its proprietary Locked Nucleic Acid (:LNA) platform and tissue-targeting expertise, Santaris Pharma is developing a diverse pipeline of LNA therapeutics that influence the production or activity of select RNA targets to address diseases which . Roche Group Diagnostics pipeline. Contact us at the Consulting WP office nearest to you or submit a business inquiry online. NOXXON PharmaGermanyListedNOXXON Pharma AG (Berlin, Germany) based on one of the biggest and best protected patent portfolios in the industry, Berlin-based NOXXON Pharma AG develops biostable aptamers, novel substances based on mirror image nucleic acids. Continue reading on Roche.com: Locked Nucleic Acid (LNA) Platform. Efficacy studies in HCV infected chimpanzee with 12 weekly intravenous dosing with miravirsen found a marked and lasting decline of the viral titer [95]. Type: Grant. Name of the organization that made the acquisition, Total amount raised across all funding rounds, Total number of employee profiles an organization has on Crunchbase, Total number of investment firms and individual investors, Descriptive keyword for an Organization (e.g. This report provides comprehensive information on the current therapeutic developmental pipeline of Santaris Pharma A/Ss, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. We have three endocrinology rare disease product candidates in clinical development, and a pipeline of oncology candidates closely following. Arexis AB, founded by experienced scientists in 1999, is a drug discovery and development company focusing on metabolic and inflammatory diseases. Thanks to their structural characteristics, Spiegelmers are extremely resistant to degradation and not immunogenic a new generation of improved therapeutics. As part of its broad patent estate, the company holds exclusive worldwide rights to manufacture, have manufactured and sell products that contain LNA as an active ingredient for studies performed with a view to obtaining marketing approval. Santaris Pharma was acquired by Roche in 2014 for $450M. Privacy Policy Santaris Pharma: Company in Denmark, Europe. Santaris Pharma is using LNA to make novel, highly potent and stable RNA Antagonists. The Company is biology-driven with proprietary technology and a strong focus on product development. After M&A, selloffs, cost cuts and therapeutic rejigs, the companies on this list may largely wear the same names, but none entered it looking exactly .. Bioventus is a global leader of innovations for active healing and surgical orthobiologics with a comprehensive portfolio of clinically efficacious and cost-effective solutions for patients . (When Cookies Enabled), Santaris Pharma A/S is a clinical stage biopharmaceutical company developing next generation RNA-silencing drugs for the treatment of cancer and metabolic diseases. Santaris Pharma has pioneered its proprietary Locked Nucleic Acid (LNA) platform that has contributed to an emerging era of RNA-targeting therapeutics. This report provides comprehensive information on the current therapeutic developmental pipeline of Santaris Pharma A/S's, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism . Associated sectors: Pharmaceuticals; Life sciences; Life Sciences - Pharma; Biotech; Life Science; Biotechnology; Healthcare - Drug development; Biopharmaceuticals; Healthtech; Healthcare; Life Sciences Companies - Drug Discovery and Development; Action PharmaDenmarkAcquiredAction Pharma A/S is a clinical stage biopharmaceutical company founded in 2000 and located in Denmark with offices and laboratories in Aarhus and Copenhagen. In addition to miravirsen, Santaris Pharma A/S has a robust product pipeline targeting mRNAs and microRNAs both internally as well as in partnerships and collaborations with . [3] This research strategy is generating a new clinical programme every year and continues to yield novel and proprietary drug targets, key to a more effective development of novel therapies. Santaris Pharma A/S was a biopharmaceutical company founded in 2003 in Copenhagen, Denmark. Action Pharma A/S is a clinical stage biopharmaceutical company founded in 2000 and located in Denmark with offices and laboratories in Aarhus and Copenhagen. The company has strategic partnerships with miRagen Therapeutics, Shire PLC, Pfizer, GlaxoSmithKline, and Enzon Pharmaceuticals. Action Pharma A/S is a clinical stage biopharmaceutical company founded in 2000 and located in Denmark with offices and laboratories in Aarhus and Copenhagen. Vaccines for veterinary and human use. Contact Email info@santaris.com Phone Number (454)517-9800 Santaris Pharma A/S is a privately held clinical-stage biopharmaceutical company focused on the discovery and development of RNA-targeted therapies. Danish Therapeutics company focused on antibody-drug conjugates (ADCs) for the treatment of cancers. [1] The company also had a branch in San Diego, California that opened in 2009. Filed: October 3, 2008. Continue reading on Roche.com: Locked Nucleic Acid (LNA) Platform If this potential is realised, even in part, it should be possible to design new drugs to treat a wide variety of human diseases by switching off the expression of harmful genes.VentureRadar Research / Company Website. It also reviews latest updates, and featured news and press releases, along with special features on late-stage and discontinued projects. Access Full Search Results with a Business Account or On Demand Pass, About Us Swiss Therapeutics company developing therapies to treat severe neurological disorders. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. SaaS, Android, Cloud Computing, Medical Device), Where the organization is headquartered (e.g. Through its partnerships with pharmaceutical companies, Santaris covers a range of therapeutic areas including cancer, cardiovascular disease, infectious and inflammatory diseases, and rare genetic disorders. Santaris Pharma A/S is a clinical- stage biopharmaceutical company focussed on developing next generation RNA-silencing drugs based on its proprietary LNA ( Locked Nucleic Acid ) technology for the treatment of cancer , metabolic diseases and gentic disorders. Our pipeline is focused on gastrointestinal, metabolic and other specialty diseases where we believe that the present standard of care is inadequate and where we have the resources to advance our peptide-based product candidates into the later stages of clinical development, including registration and commercialization, while opportunistically considering partnership relationships that may arise. Roche Innovation Center Copenhagen is the home of RNA Molecule Research, an integrated part of Roche Pharma Research and Early Development. Twitter The Roche Innovation Center in Copenhagen, originating from the acquisition of Santaris Pharma in 2014, is a leader in the rapidly emerging field of RNA-targeted drugs. Santaris Pharma is developing a diverse pipeline of LNA therapeutics that influence the production or activity of select RNA targets to address diseases that are difficult-to-treat with . Chem. The report is built using data and information sourced from proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by a team. Santaris Pharma 2007 - 2009 2 r. The core therapeutic focus of our company is obesity, Type II diabetes / metabolic syndrome, inflammatory diseases, and organ protection in severe cardiovascular diseases such as myocardial infarction and post-surgical organ failure. Zealand PharmaDenmarkListedZealand Pharma is a biotechnology company focused on the discovery, design and development of innovative peptide-based medicines. Such drugs have the potential to transform the field of RNA-targeted therapeutics, making specific and effective gene silencing a reality in human medicine. Alliance strengthens both Companies' oncology pipelines. Santaris Pharma A/S, founded in 2003, is headquartered in Denmark with operations in the United States. HORSHOLM, Denmark, July 14 -- The Board of Directors of Santaris Pharma has approved the Interim Report for the period 1 January to 30 June 2009. [2] Created by a merger between Cureon and Pantheco, Santaris developed RNA-targeted medicines using a Locked Nucleic Acid (LNA) Drug Platform and Drug Development Engine. Genentech Pipeline. Santaris Pharma A/Swas a biopharmaceutical company founded in 2003 in Copenhagen, Denmark. . Investors eagerly await updates on the pipelines of pharma/biotech companies. Santaris Pharma A/S - Product Pipeline Review - 2014 Santaris Pharma is a privately owned, clinical-stage biopharmaceutical company focused on developing a novel class of antisense drugs, termed LNA, intended to . Importantly . Sed ut perspiciatis unde omnis iste natus error sit voluptatem accusantium doloremque laudantium, totam rem aperiam. Tel. Submit a Company Downloaded by University of Colorado at Boulder on 06/07/2015 23:37:18. REVIEW View Journal | View Issue Antisense oligonucleotides: modications and clinical trials Cite this: Med. Santaris Pharma A/S - Product Pipeline Review - 2014 Published by Global Markets Direct at researchbeam.com [Report Price $1500] 39 Pages help@researchbeam.com +1-971-202-1575 | Toll Free: +1 (800)910-6452 46), and that, pursuant to the agreement, "enzon nominated six additional targets for which santaris agreed to identify lna gapmer compounds that inhibit the nominated The vaccine would be safer, easier to administer and more cost effective than other potential drug candidates currently under development. - The loss after tax realised in the 2nd quarter of 2009 was 21,6m DKK (2,9m EUR) compared to 29,8m DKK (4,0m EUR) in the 2nd quarter of 2008. Santaris Pharma AS - Pharmaceuticals & Healthcare - Deals and Alliances Profile Published by GlobalData at researchbeam.com [Report Price $250] 29 Pages help@researchbeam.com +1-971-202-1575 | Toll Free: +1 (800)910-6452 Santaris Pharma unveiled its newest microRNA therapeutic program this week having acquired intellectual property from Massachusetts General Hospital related to the use of miR-33 as a target for cardiovascular disorders including hypercholesterolemia. The top players in pharma know how to adapt. US-based Healthtech company providing remote patient monitoring solutions for COPD patients. Santaris Pharma is a biopharmaceutical company focused on the discovery and development of RNA-targeted therapies. Cookie Policy These so-called Spiegelmers (the German word Spiegel means mirror) are highly specific for the pharmacologically relevant target for which they were selected. NOXXON Pharma AG (Berlin, Germany) based on one of the biggest and best protected patent portfolios in the industry, Berlin-based NOXXON Pharma AG develops biostable aptamers, novel substances based on mirror image nucleic acids. Refresh Action Pharma A/S is a clinical stage biopharmaceutical company founded in 2000 and located in Denmark with offices and laboratories in Aarhus and Copenhagen. The company, which was created in May 2003 through the merger of Cureon A/S and Pantheco A/S, owns the exclusive worldwide rights to the use of locked-nucleic acids (LNA) in pharmaceuticals. The companys research and development activities focus on infectious diseases and cardiometabolic disorders, while partnerships with major pharmaceutical companies include a range of therapeutic areas including cancer, cardiovascular disease, infectious and inflammatory diseases, and rare genetic disorders. Santaris Pharma A/S - Product Pipeline Review - 2014 is a new market research publication announced by Reportstack. Life Sciences Companies - Drug Discovery And Development. Capabilities to rapidly deliver potent single-stranded LNA-based drug candidates across a multitude of disease states making specific and gene. Had a branch in San Diego, California that opened in 2009 company developing to Report enhances decision making capabilities and help to create effective counter strategies to gain advantage. Round type ( e.g easier to administer and more cost effective than other potential drug candidates under Updates, and featured news and press releases, santaris pharma pipeline with special on Therapeutic areas specific and effective gene silencing a reality in human medicine the discovery design. 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santaris pharma pipeline

santaris pharma pipeline